Atrial Fibrillation Warfarin, Pradaxa®, 
Xarelto®, Eliquis® 
Mechanical Heart Valves Anticoagulation
Cardio-Embolic Stroke 

Deep Vein Thrombosis 
Pulmonary Embolism 
Thrombotic Stoke
Upper or Lower Extremity Clot 

Factor V Leiden DNA Point Mutation 
Prothrombin DNA Point Mutation 
Protein C Deficiency 
Protein S Deficiency 
ATT Deficiency 

Arterial Clot 
Mesenteric Clot 
Brain Cortical Vein Clot 

Abnormal Bleeding
Platelet Disorders 

Red Cell Antibodies 
Difficult Blood Crossmatch 
Hemolytic Disease Newborn (Pregnancies/Miscarriages)

Familial Hypercholesterolemia 
LDL Cholesterol > 200
Statin = medication muscle pain, liver injury   

Thrombotic Thrombocytopenic Purpura 
Thrombotic Microangiopathy 
Antiphospholipid Syndrome 
Heparin Induced Thrombocytopenia 
Vasculitis Thrombosis 
Disseminated Intravascular Coagulopathy 

Liver Transplantation Coagulation Therapy 
Liver Disease Coagulation Therapy 
Open Heart Surgery Coagulation Therapy 

LDL Apheresis-Cholesterol Removal 
Therapeutic Apheresis 

Platelet Aggregation assays

About Dr. Thomas G. Hirose


Thomas G. Hirose M.D., F.C.A.P.

Coagulation Specialist

        Thomas G. Hirose M.D., is a coagulation specialist and serves as the Medical Director for the Laguna Hills Anticoagulation Clinic, Hemostasis & Thrombosis Center. (formally Laguna Hills Coumdin® Clinic.)  He is considered a regional and national expert concerning bleeding and clotting disorders including the appropriate use of Coumadin®, Pradaxa®, Xarelto®, and Eliquis®  for the treatment of atrial fibrillation and deep vein thrombosis. 

         Dr. Hiose completed his Transfusion Medicine Fellowship & Board Certificaiton at Harvard Medical School- New England Deaconess Hospital, Boston, Massachusetts during which he provided coagulation consultation for the Liver Transplantation & Open Heart Surgery programs. 

He completed his Internship in General Surgery University California Irvine Medical Center, Residency in Anatomic & Clinical Pathology Cedars-Sinai Medical Center and has worked as an emergency room physician.  

Dr. Hirose actively participates in the training of residents and fellows at Harbor- UCLA Medical Center.  His academic interest includes umbilical cord stems cells collection cryopreservation, as well as the clinical treatment of hypercholesterolemia utilizing LDL apheresis technology. 

Call for an appointment: 

Office: (949) 581-0555     Fax:   (949) 581-7555

Laguna Hills Anticoagulation Clinic 
formally Laguna Hills Coumadin® Clinic 
24407 Calle De La Louisa Suite 100 
Laguna Hills, CA 92653-7609